Pseudoephedrine is used to relieve nasal or sinus congestion (stuffiness) caused by the common cold, sinusitis, and hay fever and other respiratory allergies. It is also used to relieve ear congestion caused by ear inflammation or infection. It is commonly added to codeine in 'cold & flu' products. The effects of Pseudoephedrine are similar to epinephrine, and central effects are similar to, but less intense than, amphetamines. It has the potential for excitatory side effects.

Pseudoephedrine (not hydrochloride) is sparingly soluble in water, freely soluble in alcohol or ether, very soluble in benzene.


You should take special care in taking this medicine if you have any of the following conditions:

Side effects and overdose

Side effects that may require medical attention:

Side effects that usually don't require medical attention:

The LD50 for pseudoephedrine for oral administration in rats is 660mg/kg, and 371mg/kg in mice. No data regarding humans is available.

Related information: Pseudoephedrine Toxicology