Ibuprofen is a nonsteroidal antiinflammatory drug. Ibuprofen reduces inflammation and eases mild to moderate pain. It reduces fever and relieves the symptoms of rheumatism, osteoarthritis, menstrual cramps or premenstrual pain and swelling.
Ibuprofen is readily soluble in most organic solvents and very soluble in alcohol.
You should take special care in taking ibuprofen if you have any of the following conditions:
Side effects that may require medical attention:
Side effects that usually don't require medical attention:
To reduce unpleasant effects on your throat and stomach, take ibuprofen with a full glass of water and never just before lying down.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how ibuprofen affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Smoking cigarettes and drinking alcohol increase irritation to your stomach and can make it more susceptible to damage from ibuprofen.
If you get black, tarry stools or vomit up what looks like coffee grounds, call your doctor at once. You may have a bleeding ulcer.
If you are going to have surgery, tell your doctor that you are taking ibuprofen. Ibuprofen can cause blood problems. This can mean slow healing and a risk of infection. Problems can arise if you need dental work, and in the day to day care of your teeth. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
The LDLO for ibuprofen for oral administration in men is 171mg/kg. LD50 for ibuprofen for oral administration in rats is 636mg/kg.
Related information: Ibuprofen Toxicology