SolventAmount needed to dissolve
1g of caffeine
Benzene100ml; 22ml (boiling)
Ethyl alcohol66ml; 22ml (60C)
Water (pure)46ml; 5.5ml (80C); 1.5ml (100C)
Caffeine acts as a central nervous system (CNS) stimulant, increasing alertness in people who are tired or sleepy. Caffeine occurs naturally in tea, coffee, cocoa, and chocolate, and is added to many soft drinks. Sometimes caffeine is added to products containing codeine.

Caffeine is freely soluble in pyrrole, tetrahydrofuran; soluble in water, ethyl alcohol, pyridine, acetone, chloroform, ether, benzene; slightly soluble in petroleum ether.


You should take special care in taking caffeine if you have any of the following conditions:

Side effects and overdose

Side effects that may require medical attention:

Side effects that usually don't require medical attention:

The LD50 for caffeine for oral administration in humans is 150mg/kg and 192mg/kg in rats.

Related information: Coffee - Frequently Asked Question

Related information: Caffeine Toxicology